Conotruncal defects (CTD) is a kind of complicated heart disease with cyanosis and hypoxemia, including tetralogy of Fallot (TOF), transposition of the great arteries(TGA), double-outlet right ventricle (DORV), persistent truncus arteriosus (PTA), which accounts for 30% of congenital heart disease.

心脏圆锥动脉干缺损是圆锥动脉干发育障碍所造成的一类先天性心脏病，包括法洛四联症、大动脉转位、右室双出口、永存动脉干等多种导致紫绀和低氧血症的心脏复杂畸形，这类复杂心血管畸形约占先天性心脏病的30％。

Fetuses diagnosed with 22q11 micro-deletion,2 of them had tetralogy of Fallot,2 of them had aorta arch abnormality with ventricular septal defects, and one case had positive family history.

5例胎儿确诊为22q11微缺失综合征,其中2例胎儿患有法洛氏四联症,2例胎儿患有主动脉弓异常合并室间隔缺损,1例胎儿有22q11微缺失家族史。